Bioinformatics: Sequence, Structure and Databanks: A by D. Higgins, Willie Taylor

By D. Higgins, Willie Taylor

This quantity covers functional vital themes within the research of protein sequences and buildings. It comprises evaluating amino acid sequences to buildings evaluating buildings to one another, looking out details on complete protein households in addition to looking out with unmarried sequences, the way to use the web and the way to establish and use the SRS molecular biology database administration procedure. eventually, there are chapters on a number of series alignment and protein secondary constitution prediction. The booklet might be useful to occasional clients of those concepts in addition to skilled execs or researchers.

Show description

Read or Download Bioinformatics: Sequence, Structure and Databanks: A Practical Approach (The Practical Approach Series) PDF

Best bioinformatics books

Bioinformatics and Molecular Evolution

Within the present period of entire genome sequencing, Bioinformatics and Molecular Evolution presents an updated and accomplished creation to bioinformatics within the context of evolutionary biology. This available textual content: offers an intensive exam of series research, organic databases, trend popularity, and functions to genomics, microarrays, and proteomics emphasizes the theoretical and statistical tools utilized in bioinformatics courses in a manner that's obtainable to organic technology scholars areas bioinformatics within the context of evolutionary biology, together with inhabitants genetics, molecular evolution, molecular phylogenetics, and their functions gains end-of-chapter difficulties and self-tests to aid scholars synthesize the fabrics and observe their realizing is observed via a committed site - www.

Next Generation Sequencing Technologies and Challenges in Sequence Assembly (SpringerBriefs in Systems Biology)

The advent of subsequent iteration Sequencing (NGS) applied sciences led to a big transformation within the approach scientists extract genetic info from organic structures, revealing unlimited perception concerning the genome, transcriptome and epigenome of any species. even if, with NGS, got here its personal demanding situations that require non-stop improvement within the sequencing applied sciences and bioinformatics research of the ensuing uncooked info and meeting of the total size genome and transcriptome.

Intelligent Vehicular Networks and Communications: Fundamentals, Architectures and Solutions

Clever Vehicular community and Communications: basics, Architectures and options starts off with discussions on how the transportation method has reworked into today’s clever Transportation process (ITS). It explores the layout targets, demanding situations, and frameworks for modeling an ITS community, discussing vehicular community version applied sciences, mobility administration architectures, and routing mechanisms and protocols.

Additional info for Bioinformatics: Sequence, Structure and Databanks: A Practical Approach (The Practical Approach Series)

Sample text

If such projects get fully under way, which seems likely, then a complete domain fold library may be only five years away. References 1. Jones, D. , Taylor, W. , and Thornton, J. M. (1992). A new approach to protein fold recognition. Nature, 358, 86. 2. Godzik, A. and Skolnick, J. (1992). Sequence-structure matching in globular proteins: Application to supersecondaiy and tertiary structure determination. Proc. Nail. Acad. Set USA, 89,12098. 12 THREADING METHODS FOR PROTEIN STRUCTURE PREDICTION 3.

LEHTONEN given the cut-off value of 3 A, the RMSD obtained and each of the Cu-Ca atom distances contributing to the RMSD will be less than the 3 A. Alternatively, the RMSD can be calculated over all matched Cot-atom pairs, regardless of the distance between the superposed atoms. Of course, the RMSD can also be calculated between sets of any type of superposed atoms, not just Ca-atom pairs as illustrated in Protocol 4. Root mean squared deviations (RMSD) The RMSD gives a measure of the average level of deviations over the matched atoms that are included in the calculation.

Threading a database of protein cores. Proteins, 23, 356. 8. Lathrop, R. H. and Smith, T. F. (1996). J. Mol. , 255, 641. 9. Taylor, W. R. (1997). J. , 269, 902. 10. Bowie, J. , and Eisenberg, D. (1991). A method to identify protein sequences that fold into a known three-dimensional structure. Science, 253,164. 11. Taylor, W. R. and Orengo, C. A. (1989). J. Mol. , 208, 1. 12. Jones, D. T. (1998). THREADER : Protein Sequence Threading by Double Dynamic Programming. In Computational methods in molecular biology (ed.

Download PDF sample

Rated 4.78 of 5 – based on 34 votes