Genetic Engineering: Principles and Methods by Gunnar von Heijne (auth.), Jane K. Setlow (eds.)

By Gunnar von Heijne (auth.), Jane K. Setlow (eds.)

Jane ok. Setlow, PhD. has championed the sphere of genetics for over 30 years, agreeing to edit Genetic Engineering: ideas & equipment for the reason that its inception in 1979. An the world over famous scientist with a number of guides, Dr. Setlow is the previous Chairperson of the NIH Recombinant DNA Molecule Advisory Committee (RAC). Her lab can discovered at Brookhaven nationwide Laboratory, Upton, New York.

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A. (1990) in Applied Virology Research, Vol. A. ) pp. 199-221, Plenum Press, New York, NY. , Sevoian, M. and Chesebro, M. (1990) in Applied Virology Research, Vol. A. ) pp. 99-115, Plenum Press, New York, NY. , Poyry and Hovi, T. (1990) J. Gen. Virol. 71, 317-324. , de la Torre, lC. A. (1990) J. Virol. 64, 3960-3962. 36 Chao, L. (1990) Nature 348, 454-455. , Ohto, M. (1990) J. Virol, 64, 5594-5599. , Bergada, J. and Sobrino, F. (1990) Virology 179, 890-892. , Wimmer, E. J. (1990) 1 Virol. 64, 664-671.

Van Vloten-Doting, L. F. (1988) in RNA Genetics, Vol. , Holland, U. ) pp. , FL. 1. and Palese, P. (1988) in RNA Genetics, Vol. , Holland, U. ) pp. , FL. 1. A. (1988) in RNA Genetics, Vol. 1. ) pp. , FL. Zimmern, D. (1988) in RNA Genetics, Vol. 1. ) pp. , FL. H. G. (1988) Annu. Rev. Microbiol. 42, 657-683. Domingo, E. (1989) in Progress in Drug Research, Vol. ) pp. 93-133, Birkhiiuser Verlag, Basel. , Badger, 1. 1. (1989) 1. Virol. 63, 2476-2485. Temin, H. (1989) 1. AIDS 2, 1-9. , de la Torre, lC.

Or peptide vaccines produced by recombinant DNA methods and other biotecbnolo~ies. This follows from point 5 above. In addition to the limited repertoire of viral antigens of inactivated or subunit vaccines there is one important advantage of live vaccines at the population level. A live attenuated RNA virus vaccine should produce a quasispecies mutant spectrum of RNA genomes (and viral antigens) which E. DOMINGO AND J. J. HOLLAND 24 may be more representative of the quasispecies target antigens produced by "wild-type" virus or antigens in the human or'animal body.

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